BCL6 anticorps (AA 676-704)

N° du produit ABIN3030107

L’anticorps Souris Monoclonal anti-BCL6 a été validé pour WB et ELISA. Il convient pour détecter BCL6 dans des échantillons de Humain.

Aperçu rapide pour BCL6 anticorps (AA 676-704) (ABIN3030107)

Antigène: BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BCL6 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 305CT16-3-3

Détail du produit anti-BCL6 anticorps

Épitope: AA 676-704

Purification: Purified

Immunogène: A portion of amino acids 676-704 from the human protein was used as the immunogen for this BCL-6 antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Titration of the BCL-6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:250

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the BCL-6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur BCL6

Antigène: BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

Autre désignation: BCL-6

Sujet: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

UniProt: P41182

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus